Research Article
Association of Genetic Polymorphisms in TNFRSF11 with the Progression of Genetic Susceptibility to Gastric Cancer
Table 8
Clinic factors of rs9533156 polymorphism on gastric cancer development.
| Group | TC + CC | TT | OR | 95% CI | value |
| Tumor size | ≥2 cm | 360 (85.91) | 125 (80.13) | | | | <2 cm | 59 (14.09) | 31 (19.87) | 1.751 | 1.078–2.845 | 0.022 |
| Tumor location | Fundus | 6 (1.70) | 2 (1.85) | | | | Antrum | 256 (72.52) | 82 (75.93) | 0.961 | 0.190–4.853 | 0.962 | Body of the stomach | 91 (25.78) | 24 (22.22) | 0.791 | 0.150–4.171 | 0.676 |
| Tumor differentiation | Well | 12 (3.47) | 2 (1.71) | | | | Moderate | 174 (50.29) | 64 (54.70) | 2.207 | 0.481–10.132 | 0.368 | Poor | 160 (46.24) | 51 (43.59) | 1.913 | 0.414–8.830 | 0.528 |
| Pathological pattern | Signet-ring cell carcinoma | 17 (4.20) | 6 (4.55) | | | | Both | 5 (1.23) | 4 (3.03) | 0.178 | 0.183–0.991 | 0.407 | Adenocarcinoma | 383 (94.57) | 122 (92.42) | 0.903 | 0.348–2.340 | 0.833 |
| Blood glucose | Hyperglycemia | 114 (27.21) | 16 (11.51) | | | | Nonhyperglycemia | 305 (72.79) | 123 (88.49) | 2.870 | 1.635–5.048 | <0.001 |
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