Research Article

Expression of MAPK and PI3K/AKT/mTOR Proteins according to the Chronic Liver Disease Etiology in Hepatocellular Carcinoma

Table 2

Clinical outcome in HCC patients according to CLD etiology.

CriteriaAll etiologiesViral groupNonviral group value
HBVHCVAlcoholCryptogenic

Recurrence5/71 (7.0)1/10 (10.0)3/27 (11.1)1/20 (5.0)0/14 (0)0.635
Event27/71 (38.0)4/10 (40.0)11/27 (40.7)5/20 (25.0)7/14 (50.0)0.509
EFS (months)74.5 (8.5–105.2)41.0 (2.5–99.0)87.0 (39.0–120.2)75.5 (38.5–100.7)34.0 (0.0 – 109.2)0.470

Data are expressed as absolute numbers (percentage) and median (interquartile range). Number of patients with the characteristic/number for whom the information was available. HCC, hepatocellular carcinoma; CLD, chronic liver disease; HBV, hepatitis B virus; HCV, hepatitis C virus; EFS, event-free survival. The event was defined as recurrence or death from any cause since liver transplantation. Fisher’s exact test.