The Dependence between Urinary Levels of Angiogenesis Factors, 8-Iso-prostaglandin F2α, ɣ-Synuclein, and Interleukin-13 in Patients with Bladder Cancer: A Pilot Study

Table 3

Diagnostic value of examined parameters.

Diagnostic value of parameters	Se (%) (CI 95%)	Sp (%) (CI 95%)	PPV (%) (CI 95%)	NPV (%) (CI 95%)	LR+ (CI 95%)	LR− (CI 95%)
ANG (ng/mg cr.)	83.3 (71.5–91.0)	92.9 (76.5–99.1)	96.2 (86.7–99.0)	72.2 (59.4–82.2)	11.7 (3.1–44.6)	0.2 (0.1–0.3)
ANGST (ng/mg cr.)	71.7 (58.6–82.5)	96.4 (81.7–99.9)	97.7 (86.2–99.7)	61.4 (51–70.5)	20.1 (2.9–138.4)	0.2 (0.2–0.4)
8-Iso-PGF2α (ng/mg cr.)	45.0 (32.1–58.4)	96.4 (81.7–99.9)	96.4 (79.4–99.5)	45.0 (39.2–51.0)	12.6 (1.8–88.1)	0.6 (0.4–0.7)
SNCG (pg/mg cr.)	71.7 (58–82.5)	71.4 (51.3–86.8)	84.3 (74.6–90.8)	54.1 (42.5–65.2)	2.5 (1.4–4.6)	0.4 (0.2–0.6)
IL-13 (pg/mg cr.)	80.1 (67.7–89.2)	60.7 (40.6–78.5)	81.4 (73.0–87.6)	58.6 (44.1–71.8)	2.0 (1.3–3.3)	0.3 (0.2–0.6)

ANG: angiogenin; ANGST: angiostatin; 8-Iso-PGF2α: 8-iso-prostaglandin F2α; SNCG: ɣ-synuclein; IL-13: interleukin-13; Se: sensitivity; Sp: specificity; PPV: positive predictive value; NPV: negative predictive value; LR+: positive likelihood ratio; LR−: negative likelihood ratio; CI: confidence interval.