Research Article

Identification of a 5-Gene Metabolic Signature for Predicting Prognosis Based on an Integrated Analysis of Tumor Microenvironment in Lung Adenocarcinoma

Figure 1

(a) The flowchart for the process of construction and validation to the metabolic gene signature. (b) The intersection for the selected metabolic-related genes. The co-expressed genes among TCGA, GEO, and KEGG metabolism pathway datasets were prepared as metabolic-related genes for the construction of prognostic signature. (c) The heatmap to explain the different expressions between tumor and control groups. (d) The volcano plot of the 104 differentially expressed metabolic mRNAs. Red dots represent 79 upregulated mRNAs, and green dots represent 25 downregulated mRNAs.
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