RCC2 Expression Stimulates ER-Positive Breast Tumorigenesis

Figure 1

Expression of RCC2 in breast tumor tissues. (a) Western blot analysis detected an immunosignal with a molecular weight of 56 kDa in ER + breast tumor tissues (n = 13) and breast fibroadenoma (n = 7). The analysis also detected an immunosignal at a molecular weight of 37 kDa using anti-GAPDH in these tissue samples. (b) RCC2 expression was normalized with GAPDH expression. (c) Immunohistochemistry detected significant RCC2 expression in breast tumor tissues. The analysis also detected the expression of RCC2 in endothelial cells of normal breast tissues. Original magnification: 200x. (d) Semiquantification of RCC2 expression in breast tumor and healthy breast tissues. The y-axis indicates the level of RCC2 expression. .

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