Mucinous Histology, BRCA1/2 Mutations, and Elevated Tumor Mutational Burden in Colorectal Cancer

Table 5

Tumor mutation burden (TMB) of the prospective cohort. Mucinous (MC, n = 9) tumors have higher TMB versus adenocarcinoma cancers (AC, n = 5), .

	Number of patients	Average TMB (mut/megabase)	High TMB	Low TMB
Mucinous	9	43.07	3, 33%	6, 66%
Mucinous BRCA mut	4	84.03	2, 50%	2, 50%
Mucinous BRCA WT	5	10.3	1, 20%	4, 80%
Adenocarcinoma	5	5.9	0, 0%	5, 100%
Adenocarcinoma BRCA mut	2	4.91	0, 0%	2, 100%
Adenocarcinoma BRCA WT	3	6.56	0, 0%	3, 100%

Number of patients, % of patients with high/intermediate/low TMB. High TMB using standard cutoff of >20.