Research Article
Recurrent Pleomorphic Adenoma of the Parotid Gland: Experience of 128 Patients with First Recurrence
Table 2
Association between clinical pathologic variables and recurrence pattern in the 128 patients.
| | Variables | Univariate | Multivariate | | Inside (n = 93) | Outside (n = 35) | | | Or [95%CI] |
| | Age | | ≥50 | 47 (50.5%) | 20 (57.1%) | — | — | — | | <50 | 46 (49.5%) | 15 (42.9%) | 0.505 | — | — | | Sex | | Male | 42 (45.2%) | 16 (45.7%) | — | — | — | | Female | 51 (54.8%) | 19 (54.3%) | 0.955 | — | — | | Tumor rupture | | Yes | 20 (21.5%) | 10 (28.6%) | — | — | — | | No | 73 (78.5%) | 25 (71.4%) | 0.400 | — | — | | Nodule size | | ≥2.0 cm | 29 (31.2%) | 1 (2.9%) | — | — | — | | <2.0 cm | 64 (68.8%) | 34 (97.1%) | 0.001 | 0.125 | 5.415[0.875–18.632] | | Recurrence time | | <5 years | 38 (40.9%) | 10 (28.6%) | — | — | — | | ≥5 years | 55 (59.1%) | 25 (71.4%) | 0.201 | — | — | | Ki-67 | | <5.0% | 79 (84.9%) | 19 (54.3%) | — | — | — | | ≥5.0% | 14 (15.1%) | 16 (45.7%) | <0.001 | 0.014 | 2.347[1.224–5.687] | | Nodule type | | Others | 65 (69.9%) | 10 (28.6%) | — | — | — | | Cell-rich | 28 (30.1%) | 25 (71.4%) | <0.001 | 0.015 | 2.067 [1.449–6.777] | | MVD | | ≥6 | 40 (43.0%) | 18 (51.4%) | — | — | — | | <6 | 53 (57.0%) | 17 (48.6%) | 0.394 | — | — | | Primary operation | | Enucleation | 56 (60.2%) | 24 (68.6%) | — | — | — | | Partial parotidectomy | 25 (26.9%) | 8 (22.9%) | — | — | — | | Superficial parotidectomy | 12 (12.9%) | 3 (8.6%) | 0.673 | — | — |
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MVD: microvessel density. |
