Tumor-Derived Exosomal miR-620 as a Diagnostic Biomarker in Non-Small-Cell Lung Cancer

Figure 3

Exosomal miR-620 acts as a diagnostic marker in NSCLC patients. The AUC of serum exosomal miR-620 in patients with NSCLC or early-stage NSCLC and healthy donors was 0.728 (a) or 0.707 (b), respectively. The AUC of serum exosome miR-620 combined with CEA or CYFRA21-1 in NSCLC patients and healthy donors was 0.882 (c) or 0.834 (d), respectively. (e) The AUC of serum exosomal miR-620 in combination with CEA and CYFRA21-1 was 0.900 in NSCLC patients and healthy donors. The AUC of serum exosome miR-620 in combination with CEA or CYFRA21-1 in early NSCLC patients and healthy donors was 0.814 (f) or 0.761 (g), respectively. (h) The AUC of serum exosomal miR-620 in combination with CEA and CYFRA21-1 was 0.824 in early-stage NSCLC patients as well as healthy donors.

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