Research Article

Impact of Genetic Variation in TLR4 3′UTR on NSCLC Genetic Susceptibility

Table 5

Haplotype frequencies of TLR4 among cases and controls and their association with NSCLC.

HaplotypeCases (2n = 1400) 2n (%)Controls (2n = 1400) 2n (%)OR (95% CI) value

Ars1927914-Crs7869402-Trs11536891788 (56.3)787 (56.2)1.00
Grs1927914-Crs7869402-Crs1153689199 (7.1)86 (6.1)1.18 (0.87–1.59)0.283
Grs1927914-Crs7869402-Trs11536891430 (30.7)414 (29.6)1.07 (0.91–1.26)0.417
Grs1927914-Trs7869402-Trs1153689159 (4.2)100 (7.1)0.57 (0.41–0.80)0.001
Ars1927914-Crs7869402-Crs1153689116 (1.1)11 (0.8)NCNC
Ars1927914-Trs7869402-Trs115368917 (0.5)3 (0.2)NCNC
Grs1927914-Trs7869402-Crs115368910 (0.0)0 (0.0)NCNC
Ars1927914-Trs7869402-Crs115368911 (0.1)0 (0.0)NCNC

NC, not calculated.