Research Article

Defining the Ideal Patient with Hepatocellular Carcinoma for Second-Line Treatment

Table 3

Eligibility criteria for overall survival benefit with ramucirumab, cabozantinib, and regorafenib as the second line of treatment for HCC.

Main
 Male patients
 ECOG: 0
 Extrahepatic metastases
 HBV infection

Independent
 Age
 Alpha-fetoprotein
 Macrovascular invasion