Research Article

Circulating Tumor DNA Using Tagged Targeted Deep Sequencing to Assess Minimal Residual Disease in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy

Table 1

Demographics and pathological data of the studied cohort.

UPNAge at diagnosis (years)BaselineERHER2Ki-67 (%)Pre surg stgSurg stgpCR

137cT2(40)N1+40cT2(35)N0pT3N2aNo
263cT2(40)N0++10cT1(1)cN0ympT1cN1aNo
339cT2(24)N0+70cT0N0ypTisN0Yes
473cT2(30)N1+16cmT1(8)bN0ypT1bN1aNo
544cmT2(24)N0++60cT0N0ypCRYes
655cT2(43)N1+10cT1(12)cN0ypT1aN0No
761cT2(22)N0+90cT0N0ypCRYes
854cT3(60)N0+10cT0N0ypT1cN0No
944cT3(72)N1+45cT1(10)N0ypT1cN1aNo
1032cT3(90)N1+70cT1(12)cN0ypT3N2aNo

UPN = unique patient number. Baseline = clinical stage at diagnosis, before NACT. Pre surg stg = clinical staging before surgery and after NACT. Surg stg = pathological staging at surgery. pCR = pathological complete response.