The Influence of Systemic Inflammation Response Index on Survival Outcomes of Limited-Stage Small-Cell Lung Cancer Patients Treated with Concurrent Chemoradiotherapy
Table 1
Baseline demographics and treatment characteristics for the entire study population and per SIRI groups.
Characteristic
All patients (N = 181)
SIRI ≥ 1.93 (N = 110)
SIRI < 1.93 (N = 71)
value
Median age, y (range)
60 (33–80)
61 (33–79)
59 (36–79)
0.91
Age group, y (%)
<70 years
132 (72.9)
81 (73.6)
51 (71.8)
0.87
≥70 years
49 (27.1)
29 (26.4)
20 (28.2)
Gender, n (%)
Male
154 (85.0)
91 (82.7)
63 (88.7)
0.39
Female
27 (15.0)
19 (17.3)
8 (11.3)
ECOG-PS, n (%)
0–1
141 (71.7)
84 (76.4)
57 (80.3)
0.48
2
40 (28.3)
26 (23.6)
14 (19.7)
Smoking status, n (%)
Ex-smoker
174 (96.1)
106 (96.3)
68 (95.8)
0.90
Current smoker
7 (3.9)
4 (3.7)
3 (4.2)
Anemia, n (%)
Present
109 (60.2)
66 (60.0)
43 (60.6)
0.94
Absent
72 (39.8)
44 (40.0)
28 (39.4)
PCI, n (%)
Yes
139 (76.7)
85 (77.3)
54 (76.1)
0.79
No
42 (23.3)
25 (22.7)
17 (23.9)
TRT scheme
CFRT 54 Gy
77 (42.6)
47 (42.7)
30 (42.3)
0.86
HFRT 45 Gy
104 (57.4)
63 (57.3)
41 (57.7)
Treatment center
Baskent Un.
104 (57.4)
63 (57.3)
41 (57.7)
0.74
Mersin City Hospital
56 (30.9)
35 (31.8)
21 (29.6)
Suleyman Demirel Un.
21 (11.7)
12 (10.9)
9 (12.7)
Anemia refers to any Hb <130 g/dL for males and Hb <120 g/dL for females. Abbreviations . SIRI: systemic immune-inflammation response index; ECOG-PS, Eastern Cooperative Oncology Group performance status; PCI: prophylactic cranial irradiation; CFRT: conventionally fractionated radiotherapy; HFRT: hyperfractionated radiotherapy; Gy: gray; Un.: university.
