Upregulated Long Noncoding RNA UCA1 Enhances Warburg Effect via miR-203/HK2 Axis in Esophagal Cancer

<div>UCA1 regulated glycolysis through HK2. (a) Glucose consumption measured in EC109 cells transfected sh-UCA1. (b) Lactate production measured in EC109 cells transfected sh-UCA1. (c) Extracellular acid ratio (ECAR) measured in EC109 cells transfected sh-UCA1. (d) Glucose consumption measured in UCA1-overexpressing EC109 cells transfected with HK2 siRNA or 2-DG. (e) Lactate production measured in UCA1-overexpressing EC109 cells transfected with HK2 siRNA or 2-DG. (f) Extracellular acid ratio (ECAR) in UCA1-overexpressing EC109 cells transfected with HK2 siRNA or 2-DG. 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Journal of Oncology

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Figure 5

Figure 5: Upregulated Long Noncoding RNA UCA1 Enhances Warburg Effect via miR-203/HK2 Axis in Esophagal Cancer 