Construction of Nomograms for Predicting Lung and Bone Metastases in Patients with Intrahepatic Cholangiocarcinoma and Identification of Patients Who Can Benefit from Chemotherapy
Table 1
Demographic and clinical characteristics of intrahepatic cholangiocarcinoma patients.
Variables
With LM (82)
Without LM (1445)
With BM (70)
Without BM (1457)
Age
<45
3 (3.7)
76 (5.3)
4 (5.7)
75 (5.1)
45–65
41 (50.0)
575 (39.8)
34 (48.6)
582 (39.9)
≥65
38 (46.3)
794 (54.9)
32 (45.7)
800 (54.9)
Gender
Female
26 (31.7)
714 (49.4)
18 (25.7)
722 (49.6)
Male
56 (68.3)
731 (50.6)
52 (74.3)
735 (50.4)
Race
White
71 (86.6)
1149 (79.5)
61 (87.1)
1159 (79.5)
Black
3 (3.7)
118 (8.2)
2 (2.9)
119 (8.2)
Other
8 (9.8)
178 (12.3)
7 (10.0)
179 (12.3)
Histological grade
Well/moderate
34 (41.5)
868 (60.1)
18 (25.7)
722 (49.6)
Poor/undifferentiated
48 (58.5)
577 (39.9)
52 (74.3)
735 (50.4)
T stage
T1
16 (19.5)
508 (35.2)
23 (32.9)
501 (34.4)
T2
43 (52.4)
643 (44.5)
33 (47.1)
653 (44.8)
T3
19 (23.2)
186 (12.9)
12 (17.1)
193 (13.2)
T4
4 (4.9)
108 (7.5)
2 (2.9)
110 (7.5)
Marital status
Single
26 (31.7)
510 (35.3)
17 (24.3)
519 (35.6)
Married
56 (68.3)
935 (64.7)
53 (75.7)
938 (64.4)
N stage
N0
42 (51.2)
1048 (72.5)
43 (61.4)
1047 (71.9)
N1
40 (48.8)
397 (27.5)
27 (38.6)
410 (28.1)
Size
≤5 cm
10 (12.2)
579 (40.1)
10 (14.3)
579 (39.7)
5–10 cm
39 (47.6)
649 (44.9)
40 (57.1)
648 (44.5)
>10 cm
33 (40.2)
217 (15.0)
20 (28.6)
230 (15.8)
Intrahepatic metastasis
No
56 (68.3)
1390 (96.2)
55 (78.6)
1391 (95.5)
Yes
26 (31.7)
55 (3.8)
15 (21.4)
66 (4.5)
LM: lung metastasis, BM: bone metastasis, n (%) for categorical variables.
