Prognostic Significance of the Tumor-Stromal Ratio in Invasive Breast Cancer and a Proposal of a New Ts-TNM Staging System

Figure 1

IHC staining and HE staining results in TMAs. IHC staining of CK could specifically label tumor areas with clear contrast (a, b). The differentiation of tumor and stroma in HE staining was not as clear (c, d). Examples of low TSR (high stroma) (a, c); examples of high TSR (low stroma) (b, d). HE,hematoxylin-eosin; IHC, immunohistochemistry; CK, cytokeratin; TSR, tumor-stromal ratio.

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