FGFR4 c.1162G > A (p.Gly388Arg) Polymorphism Analysis in Turkish Patients with Retinoblastoma

Table 4

Distribution of FGFR4 p.Gly388Arg (c.1162G > A) variant in patients, relatives, and control group.

FGFR4 p.Gly388Arg (c.1162G > A)	Patients no. (%)	Relatives no. (%)	Control no. (%)	Total no. (%)	Significance, p value
Wild-type GG	22 (21.2%)	6 (5.7%)	76 (73.1%)	104 (50%)	0.86
Heterozygous GA	22 (26.2%)	5 (6%)	57 (67.8%)	84 (40.4%)
Homozygous AA	5 (25%)	2 (10%)	13 (65%)	20 (9.6%)
Total	49	13	146	208

Wild-type GG allele; c. [1162G > G]; [1162G > G], heterozygous GA allele; c. [1162G > G]; [1162G > A], homozygous AA; c. [1162G > G]; [1162A > A].