ZC3H13 Inhibits the Progression of Hepatocellular Carcinoma through m⁶A-PKM2-Mediated Glycolysis and Enhances Chemosensitivity

Figure 5

ZC3H13 weakens metabolism reprogramming of HCC cells. (a, b) Quantification of glucose uptake of Hep3B as well as HUH-7 cells with ZC3H13 deficiency and overexpression. (c, d) Quantification of lactate production of Hep3B as well as HUH-7 cells with ZC3H13 deficiency and overexpression. (e–i) Western blotting detecting the expression of metabolism reprogramming-related proteins including GLUT, LDHA, LDHB, and PKM2 in Hep3B as well as HUH-7 cells with overexpressed ZC3H13. ; ; and .

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