ZC3H13 Inhibits the Progression of Hepatocellular Carcinoma through m<sup>6</sup>A-PKM2-Mediated Glycolysis and Enhances Chemosensitivity

<div>PKM2 knockdown weakens cell proliferation and metabolic reprogramming mediated by ZC3H13 in HCC cells. (a) RT-qPCR detecting the mRNA expression of PKM2 for Hep3B as well as HUH-7 cells transfected by siRNAs against PKM2. (b, c) CCK-8 examining the effects of PKM2 knockdown on cell growth for Hep3B as well as HUH-7 cells with ZC3H13 loss. (d, e) The effects of silencing or overexpressing PKM2 on clone formation of Hep3B as well as HUH-7 cells with ZC3H13 knockdown. 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Journal of Oncology

fig7

Figure 7

Figure 7: ZC3H13 Inhibits the Progression of Hepatocellular Carcinoma through m<sup>6</sup>A-PKM2-Mediated Glycolysis and Enhances Chemosensitivity 

Journal of Oncology

ZC3H13 Inhibits the Progression of Hepatocellular Carcinoma through m6A-PKM2-Mediated Glycolysis and Enhances Chemosensitivity

Figure 7

ZC3H13 Inhibits the Progression of Hepatocellular Carcinoma through m⁶A-PKM2-Mediated Glycolysis and Enhances Chemosensitivity