A Novel Four-Gene Signature as a Potential Prognostic Biomarker for Hepatocellular Carcinoma

Table 3

The correlation of HCC clinic pathological variables with gene expression level in tissue samples.

Clinic pathological features	Low risk (n = 20)	High risk (n = 20)	-value
Age (years)
<60	13	8	0.113
≥60	7	12
Gender
Male	15	13	0.49
Female	5	7
Smoking
Yes	14	7	0.027
No	6	13
Alcohol
Yes	16	8	0.01
No	4	12
AFP level (ng/L)
≤400	8	16	0.01
>400	12	4
Microvascular invasion
Yes	13	6	0.027
No	7	14
TNM stage
I-II	8	6	0.507
III-IV	12	14

HCC, hepatocellular carcinoma; TNM, tumor, lymph node and metastasis.