SPP1 Regulates Radiotherapy Sensitivity of Gastric Adenocarcinoma via the Wnt/Beta-Catenin Pathway

Table 2

Univariate and multivariable analysis of prognostic factors for 5-year survival in GAC.

Variables	Univariate analysis		Multivariate analysis
	HR (95% CI)	value	HR (95% CI)	value
Gender	1.345 (0.899–2.012)	0.150
Age	1.335 (0.894–1.995)	0.158
Tumor location	1.258 (0.972–1.628)	0.081
Tumor size (cm)	1.216 (0.889–1.662)	0.221
Histological grade	1.782 (1.195–2.657)	0.005	1.051 (0.288–3.842)	0.940
Lymphatic/venous invasion	1.605 (1.072–2.404)	0.022	0.616 (0.183–2.076)	0.434
Depth of invasion	1.471 (1.151–1.878)	0.002	0.511 (0.283–0.921)	0.025
Nodal status	1.672 (1.288–2.171)	<0.001	1.432 (0.820–2.502)	0.001
SPP1 expression	2.399 (1.560–3.687)	<0.001	3.303 (1.673–6.523)	0.001