Research Article
The lncRNA B3GALT5-AS1 Functions as an HCC Suppressor by Regulating the miR-934/UFM1 Axis
Figure 5
B3GALT5-AS1 targeted miR-934 directly and negatively regulated miR-934. (a) The wild-type (wt) and mutant-type (mut) complementary sequences of the B3GALT5-AS1 with miR-934. (b) Luciferase assays of HCC cells cotransfected with the pGL3-B3GALT5-AS1-wt or pGL3-B3GALT5-AS1-mut and miR-NC or miR-934. (c) RIP assay revealed that there was specific bind locations of B3GALT4-AS1 on miR-934. (d) The miR-934 expression in HCC tissues and adjacent normal tissues. (e) miR-934 expression in the L02 cell line and five liver cancer cell lines (Hep3B, Focus, YY-8103, HCLM3, and Huh7). (f, g) Expression of miR-934 of the NC group and B3GALT5-AS1 ov group in HCCLM3 cells and the si-NC group and si-B3GALT5-AS1 group in Hep3B cells. ; .
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