Research Article

The lncRNA B3GALT5-AS1 Functions as an HCC Suppressor by Regulating the miR-934/UFM1 Axis

Figure 8

UFM1 downregulation reverses the inhibiting effect of miR-934 inhibitor in HCCLM3 cells. (a) UFM1 mRNA expression of inhibitor NC, miR-934 inhibitor, and miR-934 inhibitor + si-UFM1 groups. Cell viability detected by CCK-8 assay (b) and BrdU assay (c). (d) Cell colony formation assay of each group. (e) Apoptosis assays analyzed by flow cytometric provided that si-UFM1 could reverse the enhanced cell apoptosis ability brought by miR-934 inhibitor. The migration (f) and the invasion (g) ability of HCCLM3 cells. (h) Wound-healing assays exhibited augmented healing ratio in the cotreatment group than in solo miR-934 inhibitor-treated group. ; .
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