Metformin Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma through Circ_0003214-Mediated MiR-489-3p-ADAM10 Pathway

Table 1

Correlation between the expression of circ_0003214 and clinicopathologic features in patients with hypopharyngeal squamous cell carcinoma.

Parameters	N = 32	Circ_0003214 expression		value
		High N = 17	Low N = 15
Age, years
<60	12	5	7	0.314
≥60	20	12	8
Sex
Male	17	9	8	0.982
Female	15	8	7
TNM stage
I-II	21	7	14	0.002
III	11	10	1
Lymph node metastasis
No	24	10	14	0.024
Yes	8	7	1

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