Research Article
Outcomes of Image-Guided Moderately Hypofractionated Radiotherapy for Stage III Non-Small-Cell Lung Cancer
Table 2
Univariate and multivariate analyses of OS in the 143 stage III NSCLC patients.
| | Characteristics | Univariate analysis | Multivariate analysis | | HR | 95% CI | | HR | 95% CI | |
| | RT modality | | Hypo-RT | 1 | | | 1 | | | | Con-RT | 1.89 | 1.15–3.57 | 0.040 | 1.87 | 1.20–3.56 | 0.046 | | Age | | <65 | 1 | | | | | | | ≥65 | 1.49 | 0.76–2.94 | 0.249 | NA | | | | Gender | | Male | 1 | | | | | | | Female | 0.51 | 0.12–2.11 | 0.351 | NA | | | | Tumor stage | | IIIB | 1 | | | 1 | | | | IIIA | 0.50 | 0.26–0.97 | 0.041 | 0.57 | 0.29–1.12 | 0.103 | | PS | | 0 | 1 | | | | | | | 1 | 0.86 | 0.46–1.58 | 0.618 | NA | | | | Pathology | | Adenocarcinoma | 1 | | | 1 | | | | Nonadenocarcinoma | 2.75 | 1.27–5.95 | 0.010 | 2.7 | 1.24–5.87 | 0.012 | | Chemotherapy type | | Concurrent | 1 | | | | | | | Sequential | 1.11 | 0.60–2.05 | 0.743 | NA | | |
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OS: overall survival; NSCLC: non-small-cell lung cancer; RT: radiation therapy; Hypo-RT: hypofractionated RT; Con-RT: conventional RT; PS: performance status.
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