Research Article
miR-193a Directly Targets PSEN1 and Inhibits Gastric Cancer Cell Growth, the Activation of PI3K/Akt Signaling Pathway, and the Epithelial-to-Mesenchymal Transition
Figure 2
miR-193a suppresses the activation of PI3K/AKT pathway in gastric cancer cells. (a) miR-193a expression was low in GES-1 cells versus HGC-27 and MGC-803 cells. (b) The miR-193a mimic and miR-193a inhibitor were conducted to upregulate or downregulate miR-193a in HGC-27 cells measured by RT-qPCR. (c) CCK8 assay indicated miR-193a mimic suppressed cell proliferation, while miR-193a inhibitor promoted cell proliferative ability in HGC-27 cells. (d) miR-193a inhibited the activation of PI3K/AKT pathway. ; .
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