Research Article
PD-1/PD-L1 Inhibitors versus Chemotherapy for Previously Treated Advanced Gastroesophageal Cancer: A Meta-Analysis of Randomized Controlled Trials
Table 4
The sensitivity analyses of the study.
| | Sensitivity analyses | No. of studies | RR (95%CI) | HR (95%CI) | | No. of patients | ORR | No. of patients | PFS | No. of patients | OS |
| | Total studies | 6 | 2648 | 1.39 (0.85∼2.25) | 2648 | 1.14 (0.88∼1.46) | 2648 | 0.85 (0.75∼0.97) | | JAVELIN Gastric 300 excluded | 5 | 2277 | 1.55 (0.94∼2.55) | 2277 | 1.05 (0.81∼1.35) | 2277 | 0.82 (0.73∼0.92) | | KEYNOTE-061 excluded | 5 | 2056 | 1.54 (0.88∼2.71) | 2056 | 1.07 (0.81∼1.43) | 2056 | 0.83 (0.71∼0.98) | | KEYNOTE-181 excluded | 5 | 2020 | 1.28 (0.71∼2.28) | 2020 | 1.4 (0.83∼1.58) | 2020 | 0.84 (0.71∼1.00) | | ATTRACTION-3 excluded | 5 | 2229 | 1.51 (0.83∼2.72) | 2229 | 1.15 (0.85∼1.56) | 2229 | 0.87 (0.75∼1.10) | | ESCORT excluded | 5 | 2200 | 1.16 (0.77∼1.76) | 2200 | 1.26 (1.04∼1.53) | 2200 | 0.89 (0.78∼1.01) | | ORIENT-2 excluded | 5 | 2458 | 1.31 (0.76∼2.25) | 2458 | 1.16 (0.87∼1.55) | 2458 | 0.87 (0.76∼1.00) |
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