circ_0075943 Dominates the miR-141-3p/AK2 Network to Support the Development of Breast Carcinoma

Figure 7

Exhaustion of circ_0075943 restrained tumor growth in vivo. (a) The tumor volume is measured once a week to assess tumor growth. (b) Measure tumor weight to assess tumor growth. (c) Representative image of tumor tissue. (d) miR-141 level-3p and circ_0075943 in tumor specimen were checked by real-time PCR. (e) The immunoblotting technique checks the AK2 level in the tumor specimen. Silence circ_0075943 reduces AK2 expression. (f) Histological analysis of different groups of the specimen by HE staining. (g) The immunohistochemical method was adopted to check Ki-67 in tumor specimens of each group. Silencing circ_0075943 reduced the proliferation ability of BC cells. .

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