Research Article

MiR-145-5p Inhibits the Invasion of Prostate Cancer and Induces Apoptosis by Inhibiting WIP1

Figure 4

MiR-145-5p targeted binding to WIP1. (a) Information maps of miR-145-5p binding site with WIP1. (b) Dual-luciferase reporter gene demonstrating the binding of miR-145-5p to WIP1. (c) LNCaP cell level showing that miR-145-5p overexpression inhibits WIP1 and inhibits miR-145-5p upregulation of WIP1. (d) PC3 cell level showing that overexpression of miR-145-5p inhibits WIP1 and inhibits miR-145-5p upregulation of WIP1. (e) WIP1 is upregulated in PCa. (f) Detection of the correlation between miR-145-5p and WIP1 co-expression. and .
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