MiR-200b Suppresses Gastric Cancer Cell Migration and Invasion by Inhibiting NRG1 through ERBB2/ERBB3 Signaling

Figure 3

MiR-200b targeted NRG1. (a) Display of the NRG1 3'UTR-WT or -MUT sequences with miR-200b sequences. (b) Luciferase activity of NRG1 3'UTR-WT or -MUT in HEK-293T cells after increasing or decreasing miR-200b. (c) Protein level of NRG1 and (d) mRNA expression of NRG1 detected in GC cells after increasing or decreasing miR-200b. (e) Relationship between miR-200b expression and NRG1 expression (, ).

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