Depression Induced by CUMS Leads to Bladder Cancer Development and Local Tumor Immunosuppression in Mice

Table 3

Frequency of CD4⁺T cells and CD8⁺T cells and the ratio of CD8⁺T cells/CD4⁺T cells.

	CD4^+T cells (%)	CD8^+T cells (%)	Ratio of CD8^+T cells/CD4^+T cells
Control group (n = 5, mean ± SD)	2.83 ± 0.38	2.53 ± 0.18	0.936 ± 0.082
CUMS group (n = 5, mean ± SD)	4.15 ± 0.50	1.91 ± 0.11	0.489 ± 0.066

Frequency of CD4⁺T cells and CD8⁺T cells was measured through immunohistochemistry, and the ratio was calculated. CUMS decreased the frequency of CD8⁺T cells and the ratio of CD8⁺T cells / CD4⁺T cells. , frequency of CD4⁺T cells, CUMS group vs control group; , frequency of CD8⁺T cells, CUMS group vs control group; , the ratio of CD8⁺T cells/CD4⁺T cells, CUMS group vs control group.