A Diagnostic Analysis Workflow to Optimal Multiple Tumor Markers to Predict the Nonmetastatic Breast Cancer from Breast Lumps

Table 3

Diagnostic performance of serum biomarkers in discriminating breast cancer from benign breast diseases.

Markers	Cut-off point	AUC	Sensitivity	Specificity
CEA	0.443	0.716	0.64	0.669
Ca 15-3	0.5	0.648	0.387	0.85
CYFRA 21-1	0.471	0.761	0.64	0.805
AFP	0.433	0.577	0.604	0.549
FERR	0.647	0.592	0.27	0.902