Exosomes Derived from RM-1 Cells Promote the Recruitment of MDSCs into Tumor Microenvironment by Upregulating CXCR4 via TLR2/NF- Pathway

Figure 1

Identification of exosomes derived from RM-1. (a) Biomarkers CD63, HSP70, and TSG101 expression in exosomes detected by Western blot. Exosomes-depleted supernatant was set as the control group. (b) Purified exosomes observed by electron microscopy after ultrafiltration centrifugation; result showed exosomal pallet-like lipid bilayer vesicles and the average diameter was among 30–80 nm. The scale bar is 100 nm.

(a)

(b)