Osthole Inhibits Breast Cancer Progression through Upregulating Tumor Suppressor GNG7

Figure 2

Identification of GNG7 as a novel target of OST in BrCa. (a, b) Volcano map and heatmap of DEGs between control and OST-treated MCF-7 cells. (c) Hub genes screening and MCC scores in PPI network. (d) OST upregulated GNG7 in a time-dependent manner in MCF-7 cells. (e) OST upregulated GNG7 in a dose-dependent manner in MCF-7 cells. (f) OST upregulated GNG7 in MDA-MB-231 cells treated with 40 μmol for 24 h.

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