Research Article
Identification of a Novel Metastasis-Related miRNAs-Based Signature for Predicting the Prognosis of Hepatocellular Carcinoma
Table 1
Clinicopathological characteristics of training cohort and validation cohort.
| | | Overall | Training cohort | Validation cohort | |
| | n | 344 | 172 | 172 | | | Age (mean (SD)) | 59.35 (13.19) | 60.21 (13.30) | 58.50 (13.07) | 0.23 | | Gender = male (%) | 236 (68.6) | 118 (68.6) | 118 (68.6) | 1 |
| | Pathology grade (%) | | 0.406 | | G1 | 53 (15.4) | 25 (14.5) | 28 (16.3) | | G2 | 160 (46.5) | 83 (48.3) | 77 (44.8) | | G3 | 114 (33.1) | 52 (30.2) | 62 (36.0) | | G4 | 13 (3.8) | 9 (5.2) | 4 (2.3) | | Unknown | 4 (1.2) | 3 (1.7) | 1 (0.6) |
| | Clinical stage (%) | | 0.575 | | Stage I | 162 (47.1) | 74 (43.0) | 88 (51.2) | | Stage II | 77 (22.4) | 42 (24.4) | 35 (20.3) | | Stage III | 3 (0.9) | 2 (1.2) | 1 (0.6) | | Stage IIIA | 59 (17.2) | 30 (17.4) | 29 (16.9) | | Stage IIIB | 9 (2.6) | 4 (2.3) | 5 (2.9) | | Stage IIIC | 9 (2.6) | 4 (2.3) | 5 (2.9) | | Stage IV | 1 (0.3) | 0 (0.0) | 1 (0.6) | | Stage IVB | 2 (0.6) | 2 (1.2) | 0 (0.0) | | Unknown | 22 (6.4) | 14 (8.1) | 8 (4.7) |
| | T classification (%) | | 0.711 | | T1 | 169 (49.1) | 80 (46.5) | 89 (51.7) | | T2 | 82 (23.8) | 45 (26.2) | 37 (21.5) | | T2a | 1 (0.3) | 0 (0.0) | 1 (0.6) | | T2b | 1 (0.3) | 0 (0.0) | 1 (0.6) | | T3 | 42 (12.2) | 23 (13.4) | 19 (11.0) | | T3a | 26 (7.6) | 12 (7.0) | 14 (8.1) | | T3b | 7 (2.0) | 2 (1.2) | 5 (2.9) | | T4 | 13 (3.8) | 8 (4.7) | 5 (2.9) | | TX | 1 (0.3) | 1 (0.6) | 0 (0.0) | | Unknown | 2 (0.6) | 1 (0.6) | 1 (0.6) |
| | M classification (%) | | 0.455 | | M0 | 248 (72.1) | 119 (69.2) | 129 (75.0) | | M1 | 3 (0.9) | 2 (1.2) | 1 (0.6) | | MX | 93 (27.0) | 51 (29.7) | 42 (24.4) |
| | N classification (%) | | 0.407 | | N0 | 241 (70.1) | 115 (66.9) | 126 (73.3) | | N1 | 3 (0.9) | 1 (0.6) | 2 (1.2) | | NX | 99 (28.8) | 55 (32.0) | 44 (25.6) | | Unknown | 1 (0.3) | 1 (0.6) | 0 (0.0) |
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