A Risk Signature with Nine Stemness Index-Associated Genes for Predicting Survival of Patients with Uterine Corpus Endometrial Carcinoma

Figure 5

Validation of the risk signature in the testing and entire cohorts. (a) The risk score map (top), survival status map (middle), and gene expression heat map (bottom) of patients in the high-risk and low-risk groups in the testing cohort. (b) The risk score map (top), survival status map (middle), and gene expression heat map (bottom) of patients in the high-risk and low-risk groups in the entire cohort. The green curve in the risk score map represents the risk score of the low-risk group, and the red curve represents the risk score of the high-risk group. The green dots in the survival status map represent samples whose survival state is alive, while red dots represent samples whose survival state is dead. In the gene expression heat map, red represents high expression and blue represents low expression; color intensity represents the magnitude of the difference in gene expression. (c) Kaplan–Meier survival and ROC curves of our risk signature in the testing cohorts. (d) Kaplan–Meier survival curves of our risk signature and that of Liu in the entire cohort. (e) ROC for evaluating the predictive performance of our risk signature and that of Liu in predicting the 1-, 3-, and 5-year overall survival rates of patients in the entire cohorts. AUC: area under the curve; ROC: receiver operating characteristic curve.

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