N1, N12-Diacetylspermine Is Elevated in Colorectal Cancer and Promotes Proliferation through the miR-559/CBS Axis in Cancer Cell Lines

Table 1

Distribution of DiAcSpm status in CRC according to clinicopathological characteristics.

Characteristics	Number of patients	DiAcSpm low expression	DiAcSpm high expression
Age
<60	39	10	29	0.2490
≥60	57	21	36
Gender
Female	41	13	28	0.9158
Male	55	18	37
TNM stage
I + II	56	25	31	0.0022
III + IV	40	6	34
Tumor status
T1 T2	26	9	17	0.7667
T3 T4	70	22	48
Nodal status
Negative	67	26	41	0.0380
Positive	29	5	24
Differentiation
Poor	16	2	14	0.065
Moderate	52	22	30
Well	9	2	7
Ki-67
Low expression	36	18	18	0.0041
High expression	60	13	47