Identification of a Four-lncRNA Prognostic Signature for Colon Cancer Based on Genome Instability

Figure 3

Identification of the genome-instability-related lncRNA prognostic signature (GIRlncPSig) in the training set. (a) Eight lncRNAs were found to have a close relationship with OS of colon cancer patients with univariate Cox analysis. (b) Kaplan–Meier curves showing the OS of patients in the training set. (c) Time-dependent ROC curves of GIRlncPSig at three years. (d) The distribution of somatic mutations, MLH1 expression, and lncRNA expression with increasing risk score. (e) Total somatic mutations and (f) the MLH1 expression in the high- and low-risk groups in the training set. Validation of the GIRlncPSig in the testing set.

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