Research Article

Pinin Induces Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma by Regulating m6A Modification

Figure 1

Pinin is highly expressed in HCC and associated with EMT. (a) Immunohistochemical staining of Pinin in normal liver tissues and the hepatocellular carcinogenesis sample. (b) TCGA data on Pinin expression in normal liver tissues and tumor samples. TPM: Transcripts Per Kilobase of the exon model per million mapped reads. (c) Kaplan–Meier survival analysis was used to estimate overall survival differences. (d) Kaplan–Meier survival analysis was used to estimate disease-free survival differences. (e) Pinin expression in different pathological grade groups. (f) Gene set enrichment analysis (GSEA) was conducted to enrich Pinin-related pathways. All data were represented as mean ± SEM; , , and .
(a)
(b)
(c)
(d)
(e)
(f)