Pinin Induces Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma by Regulating m6A Modification

<div>Pinin promotes snail1 expression. (a) m6A level of mRNA quantified by LC-MS/MS. (b) Western blot to detect the expression of Pinin and snail1. (c) Coexpression analysis of SNAI1 and Pinin by using the TCGA dataset. (d) Representative image of immunofluorescence. The cells with or without Pinin overexpression were fixed. Localization of Mettl3 and RBM25 (nuclear speckle maker [<a href="/journals/jo/2021/7529164/#B33">33</a>, <a href="/journals/jo/2021/7529164/#B34">34</a>]) was detected by anti-Mettl3 and anti-Pinin antibodies. 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Journal of Oncology

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Figure 5

Figure 5: Pinin Induces Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma by Regulating m6A Modification 