Hsp70 Promotes SUMO of HIF-1α and Promotes Lung Cancer Invasion and Metastasis

Figure 3

Cell level proves that knocking down Hsp70 inhibits the malignant behavior of lung cancer cells. (a) Detection of the expression level of Hsp70 in NCI-H446 cells. (b) Detection of Hsp70 expression level in A549 cells. (c) EdU detects the effect of Hsp70 on the proliferation of NCI-H446 (magnification 400x). (d) EdU detects the effect of Hsp70 on the proliferation of A549 (magnification 400x). (e) Scratch test to detect the effect of Hsp70 on the migration of NCI-H446 cells (magnification 200x). (f) Scratch test to detect the effect of Hsp70 on the migration of A549 cells (magnification 200x). (g) Transwell detects the influence of Hsp70 on the invasion ability of NCI-H446 (magnification 200x). (h) Transwell detects the influence of Hsp70 on the invasion ability of A549 (magnification 200x). (i) qRT-PCR detects the effect of knockdown of Hsp70 on the expression of E-cadherin. (j) qRT-PCR detects the effect of knockdown of Hsp70 on Vimentin expression. , .

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