Research Article

Overall Survival Analyses following Adjuvant Chemotherapy or Nonadjuvant Chemotherapy in Patients with Stage IB Non-Small-Cell Lung Cancer

Table 1

Baseline characteristics of the study population.

Nonadjuvant chemotherapy (n = 14578)Adjuvant chemotherapy (n = 2187) value

Gender0.099
 Male6961 (47.8%)1003 (45.9%)
 Female7617 (52.2%)1184 (54.1%)

Age<0.001
 <602090 (14.3%)564 (25.8%)
 61–757489 (51.4%)1322 (60.4%)
 ≥754999 (34.3%)301 (13.8%)

Race0.533
 White12372 (84.9%)1836 (84.0%)
 Black1184 (8.1%)187 (8.6%)
 Others1022 (7.0%)164 (7.4%)

Marital status<0.001
 Divorced1649 (11.3%)266 (12.2%)
 Married8193 (56.2%)1328 (60.7%)
 Others4736 (32.5%)593 (27.1%)

Laterality0.005
 Left6059 (41.6%)840 (38.4%)
 Right8519 (58.4%)1347 (61.6%)

Grade<0.001
 Well/moderate8729 (59.9%)1132 (51.8%)
 Poor/undifferentiated4919 (33.7%)935 (42.7%)
 Unknown930 (6.4%)120 (5.5%)

Pathological subtype<0.001
 Adenocarcinoma6103 (41.9%)1027 (47.0%)
 Squamous cell carcinoma3581 (24.5%)411 (18.8%)
 Others4894 (33.6%)749 (34.2%)

Visceral pleural invasion0.452
 No5869 (40.3%)862 (39.4%)
 Yes8709 (59.7%)1325 (60.6%)

Tumor size (mm)0.002
 ≤203494 (24.0%)470 (21.5%)
 21–303355 (23.0%)472 (21.6%)
 31–407729 (53.0%)1245 (56.9%)

Surgical procedure0.005
 Lobectomy11723 (80.4%)1814 (82.9%)
 Segmentectomy2855 (19.6%)373 (17.1%)

No. of resected lymph nodes0.938
 01442 (9.9%)214 (9.8%)
 1–32541 (17.4%)370 (16.9%)
 ≥49877 (67.7%)1495 (68.4%)
 Unknown718 (4.9%)108 (4.9%)