Long Noncoding RNA LINC00526 Represses Glioma Progression via Regulating miR-5581-3p/BEX1

Figure 3

LINC00526 and BEX1 could bind with miR-5581-3p. (a) The shared binding sites for LINC00526 and BEX1 in miR-5581-3p. (b) Relative luciferase activity for glioma cells in transfection by mi-NC or miR-5581-3p mimic and wt-LINC00526 or mt-LINC00526. (c) Relative luciferase activity for glioma cells in transfection by mi-NC or miR-5581-3p mimic and wt-BEX1 or mt-BEX1. (d) RIP experiments for LINC00526, miR-5581-3p, and BEX1 coenrichment. (e) Expressions of miR-5581-3p in glioma tissues and normal tissues. (f) Expressions of miR-5581-3p in glioma cells and the normal cells. (g) Expressions of BEX1 in glioma tissues and normal tissues. (h) Expressions of BEX1 in glioma cells and the normal cells. miR-5581-3p: microRNA-5581-3p; wt: wild-type; mt: mutant; BEX1: brain-expressed X-linked 1; mi-NC: negative control miRNA.

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