Plumbagin Enhances the Radiosensitivity of Tongue Squamous Cell Carcinoma Cells via Downregulating ATM

Table 1

CI of various concentrations of PL combined with four doses of IR.

SCC9		FA				CI
PL (μM)	IR (Gy) 0	1	2	4	8	1	2	4	8
0	—	0.067	0.108	0.289	0.398	—	—	—	—
1.25	0.084	0.188	0.322	0.479	0.497	0.901	0.708	0.626	0.967
2.5	0.217	0.287	0.349	0.511	0.561	0.987	0.967	0.771	0.961
5	0.488	0.498	0.521	0.587	0.655	0.949	0.977	0.946	0.979
10	0.661	0.711	0.732	0.791	0.812	0.976	0.948	0.816	0.847
CAL27		FA				CI
PL (μM)	IR(Gy) 0	1	2	4	8	1	2	4	8
0	—	0.065	0.109	0.352	0.412	—	—	—	—
1.25	0.078	0.179	0.341	0.398	0.505	0.944	0.692	0.882	1.058
2.5	0.210	0.291	0.345	0.512	0.612	0.967	0.997	0.816	0.902
5	0.473	0.501	0.526	0.652	0.668	0.929	0.968	0.802	1.007
10	0.651	0.712	0.745	0.801	0.813	0.956	0.899	0.792	0.882