LncRNA MALAT1 Accelerates Cervical Carcinoma Proliferation by Suppressing miR-124 Expression in Cervical Tumor Cells

Figure 4

LncRNA MALAT1/miR-124 axis regulates the proliferation of cervical tumor cells. (a–d) Cell viabilities and numbers of control, miR-124, and NC (negative control) groups were determined by CCK-8 assays and trypan blue staining, n = 5, and compared with the control group. , , and compared with the miR-124 group. (e–h) Linear correlation of cervical cancer cell proliferation was analyzed with miR-124 level in Hela, Caski, C-33A, and SiHa cell lines. (i, j) Cell viabilities and numbers of NC (negative control of miR-124), miR-124, miR-124 + LV-MALAT1, and miR-124 + LV-NC groups were determined by CCK-8 and trypan blue staining assays, respectively. n = 3 in each batches, compared with the NC group, compared with the miR-124 group, and compared with the miR-124 + LV-MALAT1 group. (k, l) Cell viabilities and numbers of LV-shNC, LV-shMALAT1, LV-shMALAT1 + AMO-124, and LV-shMALAT1 + AMO-NC groups were determined by CCK-8 and trypan blue staining assays, respectively. n = 3 in each batches, and compared with the LV-shNC group, and compared with the LV-shMALAT1, and and compared with the LV-shMALAT1 + AMO-124 group.

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