Bioinformatics Analysis of Potential Therapeutic Targets and Prognostic Biomarkers amid CXC Chemokines in Ovarian Carcinoma Microenvironment

Table 1

The transcription levels of CXC chemokines in different types of OC and normal ovarian tissues (ONCOMINE).

TLR	Type of ovarian cancer versus normal ovarian tissue	Fold change	value	t-test	References	PMID
CXCL1	Ovarian serous adenocarcinoma vs. normal	2.753	0.004	4.093	Adib ovarian	14760385
CXCL3	Ovarian serous surface papillary carcinoma vs. normal	−5.279	1.57E − 5	−4.912	Welsh ovarian	11158614
	Ovarian serous adenocarcinoma vs. normal	−7.691	0.004	−3.179	Yoshihara ovarian	19486012
CXCL8	Ovarian mucinous adenocarcinoma vs. normal	2.455	0.015	2.562	Lu ovarian	15161682
CXCL10	Ovarian serous adenocarcinoma vs. normal	9.290	2.38E − 5	5.697	Yoshihara ovarian	19486012
	Ovarian serous surface papillary carcinoma vs. normal	31.673	0.011	3.620	Welsh ovarian	11158614
	Ovarian serous cystadenocarcinoma vs. normal	7.751	4.65E − 4	5.346	TCGA ovarian
CXCL11	Ovarian serous cystadenocarcinoma vs. normal	2.995	1.33E − 6	9.548	TCGA ovarian
	Ovarian serous adenocarcinoma vs. normal	6.089	0.013	2.918	Yoshihara ovarian	19486012
CXCL12	Ovarian serous adenocarcinoma vs. normal	29.039	1.10E − 8	−13.783	Yoshihara ovarian	19486012
CXCL13	Ovarian carcinoma vs. normal	2.245	2.66E − 23	12.237	Bonome ovarian	18593951
	Ovarian serous cystadenocarcinoma vs. normal	2.091	2.94E − 8	10.921	TCGA ovarian
	Ovarian serous adenocarcinoma vs. normal	2.107	0.001	3.226	Yoshihara ovarian	19486012
CXCL14	Ovarian clear cell adenocarcinoma vs. normal	2.762	3.21E − 5	6.752	Hendrix ovarian	16452189
	Ovarian clear cell adenocarcinoma vs. normal	3.372	0.002	4.385	Lu ovarian	15161682
	Ovarian endometrioid adenocarcinoma vs. normal	2.683	0.035	2.097	Lu ovarian	15161682
	Ovarian carcinoma vs. normal	2.149	6.37E − 6	5.915	Bonome ovarian	18593951