LINC00665 Targets miR-214-3p/MAPK1 Axis to Accelerate Hepatocellular Carcinoma Growth and Warburg Effect

Figure 3

LINC00665 targeted miR-214-3p. (a) starBase database showed that miR-214-3p expression in HCC tissues was declined. (b) Pearson analysis of the association between the expression levels of LINC00665 and miR-214-3p in 50 HCC tissues. (c) miR-214-3p expression was measured by qRT-PCR assay. (d) Binding sites of LINC00665 and miR-214-3p. (e, f) Luciferase gene reporter and RIP assay were applied to assess the crosstalk between LINC00665 and miR-214-3p. (g) miR-214-3p expression was measured by qRT-PCR assay in sh-LINC00665/lentiv-LINC00665-treated SNU-423 cells (n = 3, ).

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