| Variables | Univariate analysis | Multivariate analysis | HR (95% CI) | value | HR (95% CI) | value |
| Sex (F/M) | 0.796 (0.452, 1.402) | 0.430 | — | — | Age (≥65/<65) | 1.641 (0.868, 3.099) | 0.127 | — | — | ECOG (1/0) | 1.221 (0724, 2.060) | 0.454 | — | — | LDH(≥250/<250 U/L) | 0.864 (0.311, 2.395) | 0.778 | — | — | CEA(≥5/<5 ng/ml) | 3.002 (1.331, 6.863) | 0.008 | 2.491 (0.942, 6.585) | 0.066 | Tumor location | | 0.266 | — | — | Upper 1/3 | reference | | | | Middle 1/3 | 1.581 (0.671, 3.729) | 0.295 | | | Lower 1/3 | 0.928 (0.467, 1.843) | 0.831 | | | Total stomach | 1.953 (0.676, 5.643) | 0.216 | | | Surgery type (total/subtotal) | 2.332 (1.378, 3.946) | 0.002 | 1.429 (0.760, 2.690) | 0.268 | Size (≥5/<5 cm) | 1.597 (0.953, 2.676) | 0.076 | 0.835 (0.468, 1.489) | 0.542 | Grade (poor/moderate) | 2.1 (1.147, 3.846) | 0.014 | 1.055(0.505, 2.203) | 0.886 | Borrmann classification | | 0.071 | | 0.151 | I | <0.001 | 0.977 | <0.001 | 0.977 | II | 0.278 (0.108, 0.719) | 0.008 | 0.212 (0.055, 0.819) | 0.024 | III | 0.567 (0.291, 1.107) | 0.096 | 0.548 (0.263, 1.140) | 0.108 | IV | reference | | reference | | pTNM(III/II) | 4.720 (1.879, 11.859) | 0.001 | 3.381 (1.156, 9.891) | 0.026 | LVI (+/−) | 1.266 (0.731, 2.194) | 0.399 | | — | PNI (+/−) | 1.490 (0.860, 2.582) | 0.155 | | — | IS | | <0.001 | | <0.001 | Low | reference | | reference | | Intermediate | 0.269 (0.144, 0.500) | <0.001 | 0.338 (0.163,0.703) | 0.004 | High | 0.067 (0.024, 0.188) | <0.001 | 0.124 (0.041, 0.375) | <0.001 |
|
|