Research Article

Combining Intravoxel Incoherent Motion Diffusion Weighted Imaging and Texture Analysis for a Nomogram to Predict Early Treatment Response to Concurrent Chemoradiotherapy in Cervical Cancer Patients

Table 3

Statistical analysis results of the texture features in cervical cancer patients (CR versus PR).

FeaturesCRPRUnivariate analysis ()Multivariate logistic regression analysis
OR95%CI

Histogram-90th percentile772.57 ± 92.85713.70 ± 108.010.007
Histogram-variance6610.00 ± 3339.545216.36 ± 2490.300.021
GLCM-correlation0.86 ± 0.040.90 ± 0.03<0.00143.789a1.450–1322.2270.030
GLCM-IMC1−0.34 ± 0.04−0.36 ± 0.040.013
GLCM-IMC20.94 ± 0.020.95 ± 0.020.006
GLRLM-LRE3.27 ± 0.624.15 ± 0.87<0.0019.7741.375–60.4570.023
GLRLM-RP0.64 ± 0.060.67 ± 0.050.008
GLRLM-RE4.84 ± 0.265.10 ± 0.29<0.001
GLSZM-ZE6.47 ± 0.366.83 ± 0.27<0.00123.7381.276–441.7070.034

aper 0.1 increment. CR: complete response; PR: partial response; OR: odds ratio; CI: confidence interval; GLCM: gray level co-occurrence matrix; GLRLM: gray level run length matrix; GLSZM: gray level size zone matrix; IMC: informational measure of correlation; LRE: long run emphasis; RP: run percentage; RE: run entropy; ZE: zone entropy.