Key Markers Involved in the Anticolon Cancer Response of CD8+ T Cells through the Regulation of Cholesterol Metabolism

Figure 3

Disease-related modules and genes. (a) Determination of the soft threshold for the adjacency matrix. The horizontal axis represents the soft threshold power, and the vertical axis represents the square of the correlation coefficient between log₂k and log₂p (k). The blue line indicates a correlation coefficient of 0.85 and a corresponding soft threshold power of 8. (b) Gene dendrogram derived from hierarchical clustering. Different modules are indicated by the colors below the dendrogram. (c) Gene significance (GS) of five modules. (d) Module–disease relationships. The modules are represented by different colors along the horizontal axis. Correlation coefficients are indicated as numbers in corresponding positions, and p values are shown in brackets along the coefficients. Red indicates higher correlation coefficients.

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