Role of miRNA-495 and NRXN-1 and CNTN-1 mRNA Expression and Its Prognostic Importance in Breast Cancer Patients

Table 3

Association of NRXN-1 mRNA expression in breast cancer cases with different clinicopathological features.

Variables	NRXN-1 mRNA expression		value
	Mean	SD
Relative expression	11.61	7.64	—
Age
≤50 years	8.75	7.98	0.0003
>50 years	14.98	8.71
Menopause
Yes	13.01	8.86	0.03
No	8.78	8.23
Lymph nodes involvement
Yes	15.70	8.96	<0.0001
No	8.40	7.37
ER status
Positive	14.05	7.83	0.03
Negative	10.52	9.11
PR status
Positive	15.29	7.43	0.005
Negative	10.18	8.98
HER2 status
Positive	12.71	8.36	0.20
Negative	10.88	9.15
TNM stages
Early stage (I & II)	3.18	1.04	<0.0001
Advanced stage (III & IV)	16.78	7.41
Distant metastases
Yes	18.72	8.28	<0.0001
No	9.37	7.81